Naive T-cell numbers after transplantation. The numbers of (A) CD4⁺ T cells and (B) CD8⁺ T cells expressing CD45RA and CD62L are reported. For DIG009, the expression of CD45RA only is used (this patient's follow-up is at another center that does not use CD62L). The CD45RA and CD62L antibodies were not used in DIG001 at early time points. The normal expression of CD45RA on CD4 and CD8 T cells has been reported.³⁷  For age 6 months the number ranged (based on 11 infants) from 1900 to 4900/mm³; for age 12 months, the range was 1100 to 4300/mm³; for adults (based on 9 individuals), the range was 100 to 800/mm³. For cells expressing CD3, CD8, and CD45RA, the range at 6 months was 500 to 1900/mm³; the range at 12 months was 600 to 1300/mm³; the range for adults was 100 to 600/mm³.