Figure 1.
HLA characteristics of transplantations from HLA-matched family donors other than genotypically HLA-identical siblings (MFD study group). HLA matches (white boxes) and HLA mismatches (black boxes) are detailed by the HLA loci (A, B, C, DRB1, and DQB1) and the immunologic vector (GVH indicates graft-versus-host; HVG, host-versus-graft). N indicates number of transplantations for a given HLA constellation. More than 95% of the given HLA mismatches were full antigen mismatches (eg, A*02 vs A*03, DRB1*01 vs DRB1*04), whereas the remaining mismatches were HLA antigen split mismatches (eg, B*15 [62] vs B*15 [63], B*40 [60] vs B*40 [61]).