Platelet accumulation onto thrombogenic devices. Platelet (PLT) accumulation was measured during the first 60 minutes of thrombus growth from the time of temporary DG, TG, or ePTFE (not displayed) device deployment at time 0 minute into chronic AV shunts. ○ indicates untreated DG or TG controls; ⋄, heparin treatment; and ▴, aFXI treatment. (A) Net PLT accumulation rates (NPAR) in the DG. (B) NPAR in the TF-dependent TG. (C) Net PLT accumulation in the DG. (D) Net PLT accumulation in the TG. Error bars correspond to 1 SD. Refer to “Results and discussion” for summary results on the limited thrombogenicity of native ePTFE.