Figure 1.
![Figure 1. αCD154 + DST delays skin graft rejection by alloreactive Tg CD4+ T cells. On day –1, C57BL/6 RAG KO mice were injected with TEa Tg T cells with or without CB6F1 spleen cells followed by a CB6F1 skin graft on day 0. Mice were treated with αCD154 or control H-Ig and scored for graft rejection 3 times per week. Grafts were considered rejected when completely necrotic, or when less than 20% of the graft remained. Data were pooled from 3 separate experiments. (▾ represents H-Ig [n = 13]; ▪, DST [n = 16]; ♦, αCD154 [n = 18]; and •, DST +αCD154 [n = 17].)](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/102/5/10.1182_blood-2003-02-0586/6/h81734878001.jpeg?Expires=1736045848&Signature=mJmcmMVzSsafS5zqrzA~7FX77veJHsJsYuU7MG1K2zPZSdaXh1K~i9nciULOr7Na6wUpJvdhLUHySeXtO5DqViyeuHvED74eUKvlojUilnNJ3wg5KbC-IA9eQtAgZX72~peX-37FPIc9ggXRKT193W7XNtGVuB0BNj4mPnRSJ0dFkjqZWxHDqtn74jcLUYarpsTJlixEvE1yt2DnzrRIYwGwchSc3x-hlOL4szIcP1~vTB7T9HBWlUS51yPUhEqm6vCxfvC4rPC0lBtjG3UUAYssyVXatUejhC4BO9OS50pkBMaP9YiSNxg2M7B9iVOxBdOet8DbP79NGtApnhGvCg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
αCD154 + DST delays skin graft rejection by alloreactive Tg CD4+ T cells. On day –1, C57BL/6 RAG KO mice were injected with TEa Tg T cells with or without CB6F1 spleen cells followed by a CB6F1 skin graft on day 0. Mice were treated with αCD154 or control H-Ig and scored for graft rejection 3 times per week. Grafts were considered rejected when completely necrotic, or when less than 20% of the graft remained. Data were pooled from 3 separate experiments. (▾ represents H-Ig [n = 13]; ▪, DST [n = 16]; ♦, αCD154 [n = 18]; and •, DST +αCD154 [n = 17].)
