Figure 2.
Structure and composition of the LckOM LN stroma. (A) Sections from B6 thymus and LN and from LckOM LN were stained with hematoxylin and labeled with antibodies specific for cytokeratin and CD62L ligand (PNAd carbohydrate epitope). The text to the right of the panels indicates the magnification for each row. (B) The number of CD62L ligand+ blood vessels per square micrometer was significantly increased in the LckOM relative to the LN (*P < .0001, Student t test). (C) Flow cytometry analyses revealed no significant difference in the proportion of DCs (MHC class II+CD11c+) between B6 (□) and LckOM (▪) secondary lymphoid organs.