DTH response induced by mBSA. (A) DTH response was induced by mBSA in mBSA-sensitized β4GalT-I^+/– (□; n = 8) and β4GalT-I^–/– (▦; n = 8) mice. The increase in footpad thickness was calculated as described in “Materials and methods.” (B) Weigert hematoxylin and eosin staining of footpad sections. (i) PBS-injected β4GalT-I^+/– mice. (ii) mBSA-injected β4GalT-I^+/– mice. (iii) PBS-injected β4GalT-I^–/– mice. (iv) mBSA-injected β4GalT-I^–/– mice. Original magnification, × 100.