CXCL12 is expressed on invasive fetal trophoblasts. Immunohistochemistry on paraformaldehyde-fixed decidual tissue (9 weeks). Immunohistochemistry was performed on first-trimester serial sections derived from placental and decidual tissues. The figure shows HLA-G (left column) and CXCL12 (right column) staining on intermediate trophoblasts (A-B), trophoblast cell islands (C-D), and invasive EVTs (E-F) derived from first-trimester deciduae. One representative staining experiment is shown of 9 performed. Arrows indicate fetal trophoblasts; **, villous cytotrophoblasts and syncytiotrophoblasts; DEC, decidua; VIL, villous; and TCI, trophoblast cell island. Magnification is × 200 for all panels.