Figure 3.
Bacitracin and bacitracin A inhibit platelet adhesion to monomeric type I collagen and GFOGER-GPP but not CRP. (A) Platelets were preincubated with up to 6 mM bacitracin for 10 minutes before adding to wells coated with the indicated substrate. Adhesion was measured after 45 minutes at room temperature. This graph contains data (mean ± SD) from 3 separate experiments, each performed in triplicate, using adhesion method A. (B) Platelets were preincubated with up to 3 mM bacitracin A for 20 minutes before adding to wells coated as indicated. Samples were measured after 1 hour at room temperature. The data (mean ± SD) are compiled from 3 experiments each performed in triplicate, using adhesion method B. Where error bars are absent, they were too small to show.