Figure 1.
Examples of intracytoplasmic expression of TNF-α and IFN-γ in CD3+BM MNCs from 2 representative FA patients (UPN 1 and 7) and 2 representative healthy control subjects. As shown in Table 2 and Figure 2, TNF-α and IFN-γ were also expressed in CD3– cells. In the top right corner of each scattergram the percentage of positive BM cells is represented. UPN 1: (A) CD3+/TNF-α+ cells, 7%; (B) CD3+/IFN-γ+ cells, 9%. UPN 7: (C) CD3+/TNF-α+ cells, 17%; (D) CD3+/IFN-γ+ cells, 20%. Healthy control 1: (E) CD3+/TNF-α+ cells, less than 1%; (F) CD3+/IFN-γ+ cells, 2%. Healthy control 2: (G) CD3+/TNF-α+ cells, less than 1%; (H) CD3+/IFN-γ+ cells, less than 1%.