Figure 2.
ZOL prevents the prenylation of Rap. Cell lysates from BV173 cells treated with 5, 10, or 20 μM ZOL for 24 and 48 hours were subjected to Western blotting using an antibody specific for the unprenylated form of Rap1A, an antibody for Ras, and for β-actin. The data shown are representative of 3 independent experiments.