Figure 3.
Aberrant collagen and convulxin-induced aggregation in GP VInull mice. Blood was withdrawn from GP VIWT, GP VIhet, and GP VInull mice. Mouse platelet-rich plasma was obtained by pooling blood from animals with the same genotype. The platelet number in each sample was normalized to 240 × 109/L with platelet-poor plasma. Indicated concentrations of acid-insoluble fibrillar collagen (type I), convulxin, and PMA were added to stirred platelets and the aggregation profiles are presented.