Figure 2.
Quantitative analysis of formation of thrombi in wild-type (▪) and FgγΔ5 (▦) arterioles. (A) The number of fluorescent platelets deposited per minute was determined in the interval of 3 to 5 minutes after injury. Fg γ chain C-terminal sequence appeared not to influence significantly the early platelet interactions with the subendothelium. (B) Thrombus formation. The time required for the formation of the first thrombus larger than 20 μm in diameter was also similar in these 2 genotypes. (C) Embolization. The number of large emboli larger than 30 μm generated in the period before occlusion was determined. About 15 times more emboli formed in FgγΔ5 mice than in wild type (Mean ± SE. wild type: n = 14; FgγΔ5: n = 18).