Thrombotic occlusion of the carotid artery following photochemically induced endothelial injury. (A) The blood flow recordings of the α₂^+/+, α₂^+/-, and α₂^-/- mice. Rose bengal dye was injected at time = 0 minutes. (B) The length of time to complete arterial occlusion following photochemical injury was determined. The values represent the mean ± SD of α₂^+/+ (n = 7), α₂^+/- (n = 6), and α₂^-/- (n = 8). (C) Photomicrographs of transverse sections of the carotid arteries of α₂^+/+ mice and α₂^-/- mice excised immediately after complete thrombosis. Sections were stained with hematoxylin and eosin; original magnification, × 200.