Figure 4.
Comparison of proliferation in response to peptide 861-874 by T cells from NZB mice that had inhaled saline, peptide 861-874 (CLAVLWVVKSTPAS), or peptide 861-875 (Glu861, Lys875). Splenic T cells were obtained from the 2 groups of animals on day 14 after treatment and stimulated with peptide 861-874. Each point represents the stimulation index of peak responses by T cells from 1 mouse (*P < .001, Mann-Whitney U test).