Figure 3.
SEM of fibrinogens. Scanning electron micrographs of normal (A) and BβArg14His (B) fibrinogens polymerized with thrombin. Clots used for scanning electron microscopy were formed with 0.4 mg/mL fibrinogen and 0.4 U/mL thrombin in 20 mM HEPES, pH 7.4, 150 mM NaCl, 1 mM CaCl2. SEM was performed as detailed in “Materials and methods.” Scale bar equals 1 μm.