Figure 2.
Decitabine increased total hemoglobin (Hb) and decreased the absolute reticulocyte count. (A) Change in Hb: 76 ± 10 to 96 ± 9 g/L (7.6 ± 1 to 9.6 ± 0.9 g/dL) (mean ± SD of pretreatment to peak Hb, 2-tailed paired t test P < .001). (B) Absolute reticulocyte counts decreased significantly: 231 × 109/L ± 98 × 109/L to 163 × 109/L ± 93 × 109/L (mean ± SD pretreat ment to after cycle 2, 2-tailed paired t test P = .0006) (error bars represent SD). There was a significant inverse correlation between hemoglobin levels and the reticulo cyte count (P < .0001).
