Representative photomicrographs showing atherosclerotic lesions in the aortic sinus of CD2-dnTGFBRII LDLr KO mice. CD1 staining was detected using antimouse goat polyclonal CD1 antibody (arrow in panel A). Only few CD1⁺ dendritic cells were detected. Although these cells expressed MHC class II (arrow in panel B), most of the MHC class II-positive cells stained negative for CD1 in an adjacent section (B). (C) MHC class II expression detected by staining with antimouse MHC class II. (D) Adjacent section stained with MOMA-2 to detect macrophages and foam cells. Most of the macrophages staining positively for MHC class II were disposed at the margins of the lipid core. Original magnification, × 400 (A-B); and × 200 (C-D).