Tissue distribution of EMR2 ligand. Multivalent probes (green) were used to examine the distribution of the EMR2 ligand in human and mouse tissues. Double staining was performed with either Hoechst stain (blue) to highlight nuclei or an antihuman collagen I antibody (red). Adjacent sections were stained with hematoxylin and eosin. (A-B) Mouse skin. (C-D) Mouse esophagus. (E-F) Human liver. (G-H) Human spleen.