Figure 5.
Figure 5. Allogeneic ALAK cells do not exert suppressive effects on lymphoid and erythroid reconstitution after BMT. B6-Ly5.2 BMCs (5 × 107) and ALAK cells (5 × 107) from B10 or B10.D2 mice were cultured for 24 hours, after which the cells were transplanted into irradiated B6 recipients (8.5 Gy) at 3 × 106 BMCs per mouse (intravenously) based on the cell numbers at the initiation of coculture, as described in “Materials and methods.” At various days after BMT, peripheral blood samples were collected from 3 mice per group, and CBCs were measured, as described in “Materials and methods.” Pooled data and SEMs from 2 independent experiments are shown. RBC indicates red blood cell.

Allogeneic ALAK cells do not exert suppressive effects on lymphoid and erythroid reconstitution after BMT. B6-Ly5.2 BMCs (5 × 107) and ALAK cells (5 × 107) from B10 or B10.D2 mice were cultured for 24 hours, after which the cells were transplanted into irradiated B6 recipients (8.5 Gy) at 3 × 106 BMCs per mouse (intravenously) based on the cell numbers at the initiation of coculture, as described in “Materials and methods.” At various days after BMT, peripheral blood samples were collected from 3 mice per group, and CBCs were measured, as described in “Materials and methods.” Pooled data and SEMs from 2 independent experiments are shown. RBC indicates red blood cell.

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