Thrombocytopenia induced by B hermsii infection is not associated with generalized activation of the coagulation cascade. C57BL6 mice were injected intraperitoneally with control buffer, LPS, or 10⁶B hermsii DAH. Two days after infection, platelet counts were determined by flow cytometry (left), and plasma fibrin D-dimer levels (right) were quantitated by ELISA (see “Materials and methods”). Shown are the means ± SDs of 5 mice. *P < .05 compared with saline; **P < .001 compared with saline.