Overall changes in gene expression induced by LMP2A. (A) The percentage of genes increased or decreased by LMP2A expression in various cell types is indicated. Gene expression in primary murine bone marrow and splenic B cells from LMP2A transgenic mice was compared with that in B cells from nontransgenic littermates. Gene expression in LMP2A-positive human B-lymphoma lines (BJAB) and EBV-transformed LCLs was compared with that in LMP2A-negative BJABs and LCLs, respectively. (B) Genes were annotated and placed in categories based on protein function. The percentages of genes in each category relative to the overall changes in gene expression are shown.