American Society of Hematology

Figure 2.

$Figure 2. B220-lo and B220-neg plasma cells are found in multiple lymphoid organs. Cervical lymph node (LN), spleen (SPL), and bone marrow (BM) cells were separated into B220-positive (+) and B220-negative (-) fractions, and the density and total number of IgG plasma cells (ASC) per tissue in each fraction was determined by ELISPOT as described in “Materials and methods.” The data are represented as the mean ± SEM. For LN, n = 5 mice, and for SPL and BM, n = 6 mice. (A) IgG ASC/106 total cells. (B) Total IgG ASC/tissue.$

B220-lo and B220-neg plasma cells are found in multiple lymphoid organs. Cervical lymph node (LN), spleen (SPL), and bone marrow (BM) cells were separated into B220-positive (+) and B220-negative (-) fractions, and the density and total number of IgG plasma cells (ASC) per tissue in each fraction was determined by ELISPOT as described in “Materials and methods.” The data are represented as the mean ± SEM. For LN, n = 5 mice, and for SPL and BM, n = 6 mice. (A) IgG ASC/10⁶ total cells. (B) Total IgG ASC/tissue.

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