Kinase and phosphatase inhibitors alter microvilli in a manner predicted by their effects on ERM phosphorylation. Scanning electron micrographs of PBT cells that were: (A) untreated; (B) treated with 500 nM staurosporine A for 30 seconds; (C) treated with 50 nM calyculin A for 5 minutes; (D) treated with SDF-1α for 30 seconds; and (E) pretreated with 50 nM calyculin A for 5 minutes before treatment with SDF-1α for 30 seconds. Bar represents 5 μm. Microvilli appear shorter in these images acquired by conventional SEM using samples dehydrated by chemical drying with tetramethylsilane rather than field emission SEM of samples dehydrated by critical point drying (Figure 1).