Hematologic profiles of OSMR^+/+, OSMR^+/–, and OSMR^–/– mice. Orbital plexus blood was collected from anesthetized mice. Peripheral red blood cells (RBCs; panel A) and platelets (B) were analyzed by using automated counter Sysmex K-4500. Numbers show mean cell number ± SD (n = 17 of OSMR^+/+ and OSMR^–/–,n = 6 of OSMR^+/– for RBCs; n = 14 of OSMR^+/+ and OSMR^–/–,n = 6 of OSMR^+/– for platelets). *P < .001 between wild-type and mutant mice.