Figure 1.
Figure 1. Effects of R115777 on the growth of 3 myeloma cell lines. The cells were cultured in quadruplicate at a density of 2.5 × 105 cells/mL in 96-well flat-bottomed tissue-culture plates with R115777 at concentrations of 0 (control) and 1.0 × 10-6 Mto1.0 × 10-12 M for 72 hours at 37°C in a humidified atmosphere of 5% CO2 in air. R115777 inhibited the growth of the U266 (A) and NCI-H929 (B) cell lines dose dependently but weakly inhibited the growth of RPMI8226 cells (C). Values represent means ± SDs of quadruplicate cultures. *P < .01.

Effects of R115777 on the growth of 3 myeloma cell lines. The cells were cultured in quadruplicate at a density of 2.5 × 105 cells/mL in 96-well flat-bottomed tissue-culture plates with R115777 at concentrations of 0 (control) and 1.0 × 10-6 Mto1.0 × 10-12 M for 72 hours at 37°C in a humidified atmosphere of 5% CO2 in air. R115777 inhibited the growth of the U266 (A) and NCI-H929 (B) cell lines dose dependently but weakly inhibited the growth of RPMI8226 cells (C). Values represent means ± SDs of quadruplicate cultures. *P < .01.

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