Figure 2.
Cytokines produced by ISS-activated PDCs are differentially inhibited by IL-10. (A) Purified PDCs (3-5 × 104) were stimulated with ISS (5 μg/mL) alone (i) or in combination with CD40L-transfected L cells (ii) for 24 to 48 hours and (B) in the presence of IL-10 (1 ng/mL). Representative results of more than 20 donors are shown.