EDN induction of human iDC migration in a PTX-sensitive manner. (A) Dose-dependent migration of CD34⁺ cell–derived iDCs in response to EDN. (B) Inhibition of EDN-induced migration of CD34⁺ cell–derived iDCs by PTX. Immature DCs were preincubated at 37°C for 30 minutes in the absence (PTX^-) and presence (PTX⁺) of PTX (200 ng/mL) before applying to the upper wells of chemotaxis chamber. DC migration is shown as the average number of migrated cells (mean ± SD) in triplicate wells.