Splenomegaly/gallstone detection; risk of iron overload. (A) Detection of splenomegaly and of gallstones. (B) Risk of iron overload dependent on age. This shows that the probability of reaching concentrations of 300 μg/mL and 1000 μg/mL (300 ng/mL and 1000 ng/mL) serum ferritin is dependent on age.