Family tree. The arrow indicates the proband. Apart from the father (II.4) who died from a presumed myocardial infarction, no history of abnormal bleeding or thrombosis was reported on either side of the family (individual II.2 died in an accident at age 34; individual II.3 died close to birth). The mother's 3 brothers (II.6, II.7, and II.8) died from reported Hurler syndrome. □ = male; ○, female; and /, deceased.