LANA enhances the transcriptional activity of a GAL4-c-Jun transactivation domain fusion. The EGFP-LANA expression plasmid (50 ng) or the vector control (50 ng) was cotransfected with either MEKK or vFLIP expression plasmids (0.1 μg) or relevant control vectors. The GAL4-c-Jun transactivation domain fusion construct and pGAL4-luc reporter plasmid (0.1 μg each) were included in all transfections. The results, which were normalized to that of the negative control group (EGFP control + control vector for MEKK/vFLIP), are the means of 3 experiments and are reported ± SD.