Lysis of primary AML blasts and malignant B-CLL cells endogenouslyexpressing OFA-iLRP. HLA-A2⁺/OFA-iLRP⁺ leukemic blasts (A; AML 1, 3, 5, 6), HLA-A2^-/OFA-iLRP⁺ blasts (B; AML 2, 4), HLA-A2⁺/OFA-iLRP⁺ B-CLL cells (C; CLL1, CLL3), and HLA-A2^-/OFA-iLRP⁺ B-CLL cells (D; CLL2, CLL4) were used as targets in a 4-hour ⁵¹Chromium release assay. One representative experiment is shown.