Etoposide and catechol on and off prednisone. In 39 of 41 patients, etoposide clearance was higher at day 29 of therapy (after 28 days of glucocorticoid) than at week 54 (A). The dose-normalized etoposide catechol plasma AUC in 28 of these patients was lower at day 29 than at week 54 (B).