Simplified overview of the events taking place during drug-induced activation of apoptotic parameters. Drugs A and B represent 2 structurally unrelated drugs. Numbers 1, 2, and 3 refer to the 3 phases of the drug-induced apoptotic route as described in “Introduction”: 1 indicates insult generation; 2, signal transduction; and 3, execution. Parameters with an asterisk (^*) are measured in this study using flow cytometry; the right column indicates the detection method used.