Overview of differential gene expression patterns in CD34 cell of AA patients compared with healthy volunteers. Gene expression profiles of CD34 cells from 2 independent pools of patients and controls were generated by means of Affymetrix Human Genome U95A version 2 arrays, and the results analyzed by GeneSpring software. A gene within each category was considered differentially expressed if at least a 2.0-fold difference was observed between AA and controls in both biologic pools. The numbers of genes in each functional category in which transcripts were more abundant in AA patients than in healthy volunteers are shown to the right, and genes less expressed in AA patients compared with controls are shown on the left.