Cleavage site choice by different prothrombin haplotypes. The percentage of cleavage site choice and the number of analyzed clones are shown for the different prothrombin haplotypes. The mRNA cleavage sites are projected on the genomic DNA sequence with the polymorphic 20210G>A site indicated. See “Results” and “Discussion” for assignment of cleavage sites. mRNA was isolated from pooled stably transfected HepG2 cells. (A) All clones analyzed. Sum is not always 100% due to rounding. (B) Subgroup analysis of clones containing correctly spliced inserts.