CsA treatments result in alterations to LPS-induced CKR expression. Murine BMDCs (day 5 DCs) were treated as indicated, harvested, and total RNA or total protein extracted. RT-PCR (A) and Western blot assay (B) were performed to examine CKR expression. (C-D) CKR expression in human MoDCs. DCs (day-6 DCs) were treated with CsA (1 μg/mL), LPS (100 ng/mL), or CsA (1 μg/mL) plus LPS (100 ng/mL) and then analyzed by Western blot (C) and FACS assays (D).