Effect of repeated administration of the small compounds on peripheral blood cell levels in normal CD rats. Male CD rats were injected subcutaneously with SSCL02446 nitrate (A), SSCL02447 nitrate (B), SSCL02448 nitrate (C), or rhG-CSF (D). Neutrophil (A-D), lymphocyte (panel E), monocyte (panel F), RBC (panel G), and platelet (panel H) counts were measured in peripheral blood. Peripheral blood cells were collected on day –2 and days 1, 2, 3, 4, 5, 6, and 8. On days 1, 2, 3 and 4, they were collected 8 hours after each administration. Other details were as described in the legend to Figure 4.