Figure 2.
Induction of γ globin gene promoter by hydroxamic acid analogues of trapoxin. (A) Data from compounds M232 (▪), M183 (▤), SW187 (▴), SW188 (•), and SW189 (
). (B) Data from compounds SW68 (▪), SW70 (▤), SW99 (•), and SW86 (
). Each data point is based on triplicate determinations done in 3 separate experiments. Except for M232, concentrations greater than those presented in the figure were toxic to the cells. Error bars indicate SEM.