Figure 4.
![Figure 4. Acute GVHD incidence is significantly reduced in SCT recipients who received donor PBSC grafts, with the lowest fractions of CD4+ and CD8+ T cells expressing CD25. (A) Actuarial incidence of acute GVHD was significantly lower in SCT patients receiving a lower fraction of CD4+CD25+ T cells than others (7% for recipients with donors in the lowest quartile of CD25 expression [solid line] vs 47% for others [dashed line]; P = .01). (B) Actuarial incidence of acute GVHD was also lower in SCT patients receiving a lower fraction of CD8+CD25+ T cells than others (13% for recipients with donors in the lowest quartile of CD25 expression [solid line] vs 44% for others [dashed line]; P = .05).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/103/3/10.1182_blood-2003-06-2085/6/zh80030455890004.jpeg?Expires=1735536718&Signature=tlxgk5xmecPmZ6I4jW4~f1lwQFmFB642nc7t6QzuNiptAS6O1BSkBiDIxTKXEnEk8f4Hj4ANLa~vIEk-rgOotdRYwtW80ZyhiUwaZEG74IlrcSBsAU~wmsvXOrFHkzkPF2Jj00pHelT8pwnbE3CprzFVbXF4W4jvr09mFhPk7-l-280pUWcW9Pmd0LCqWhkqzDqnPicW3pRFf23uxISw7kqzneg~AdZD8vHhqe-RtgYVJK7HDS-dSnqj2~j0w-j7MhWeOOvc2XfK0B~2baPT19O8zHuOyHZ7wNUCxfmpqKqZUkRXUgaHxNhyq40X0H~AZDCj1uMJEmx5XM1bupV0HQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Acute GVHD incidence is significantly reduced in SCT recipients who received donor PBSC grafts, with the lowest fractions of CD4+ and CD8+ T cells expressing CD25. (A) Actuarial incidence of acute GVHD was significantly lower in SCT patients receiving a lower fraction of CD4+CD25+ T cells than others (7% for recipients with donors in the lowest quartile of CD25 expression [solid line] vs 47% for others [dashed line]; P = .01). (B) Actuarial incidence of acute GVHD was also lower in SCT patients receiving a lower fraction of CD8+CD25+ T cells than others (13% for recipients with donors in the lowest quartile of CD25 expression [solid line] vs 44% for others [dashed line]; P = .05).
