Figure 3.
Gene expression patterns in the subset of patients harboring BCR/ABL (A) Agglomerative hierarchical clustering according to similarity in gene expression patterns. The variation in expression is displayed for the 500 clones (463 genes) for which the log2 intensity ratio differed by at least 1.5 from its mean on at least 2 arrays. The broad features of the clustering patterns were robust to variations in gene selection criteria. (B) SAM identifies genes whose expression is statistically different in the 2 groups of BCR/ABL samples (338 clones representing 314 genes, 1000 permutations, median false significant clones = 2.8), (C) selected genes identified by SAM.
