Platelet counts and fibrinogen levels in treated dogs. Blood was collected from the dogs at the times indicated prior to and following treatment. Platelet and fibrinogen levels were measured. (A) Platelet counts in dogs A (▴), B (•), C (▪), and D (♦) treated with HD-Ad vectors. (B) Fibrinogen levels in dogs treated with HD-Ad vectors (normal canine fibrinogen levels, 2-4g/L).