MOMA-1⁺ and F4/80⁺ macrophages in tissues of Csf1^op/Csf1op; TgCS5/+ mice. (A-L) Paraffin-embedded sections of spleens (A-C), adrenal medulla (D-F), synovial membrane (G-I), and liver (J-L) from 3-month-old wild-type (A,D,G,J), Csf1^op/Csf1op (B,E,H,K), and Csf1op/Csf1op; TgCS/+ mice (C,F,I,L) stained with the macrophage-specific anti-F4/80 antibody and counterstained (A-I) with hematoxylin. (M-O) Frozen spleen sections from 1-month-old wild-type (M), Csf1^op/Csf1op (N), and Csf1^op/Csf1op; TgCS/+ mice (O) stained with the marginal metallophilic macrophage-specific monoclonal antibody, MOMA-1, and counterstained with hematoxylin. MOMA-1⁺ brown dendritic cells surround the white pulp in spleen. Bars: 50 μm (A-L) and 80 μm (M-O).