Northern blot analysis confirming findings of gene array. In each lane, total bone marrow RNA (approximately 10 μg) from S mansoni–infected and uninfected wild-type and IL-5^–/^– mice as indicated, probed with (A) a 86-bp oligonucleotide probe encoding mEar-2, which will cross-react with most of the 15 known genes of the mEar cluster; (B) an 60-bp oligonucleotide probe encoding eosinophil peroxidase (EPO; see “Materials and methods”), and (C) human β-actin. Relative signals (probe/actin) determined by scanning densitometry are as follows: IL-5^–/^–/WT/:IL-5^–/^– infected/WT/infected, mEar/β-actin, 0.13:0.19:1.0:16 (16-fold over WT, 86-fold over IL-5^–/^– infected); mEPO/β-actin, 0.08:0.12:1.0:15 (15-fold over WT, 122-fold over IL-5^–/^– infected).