Figure 4.
IFN-α and IL-12 production by bone marrow–derived IPC in response to UV-inactivated HSV-1. Bone marrow–derived IPCs (5 × 105/mL, 129/SvJ strain) were incubated with untreated and UV-inactivated KOS HSV-1 at 5 and 0.5 MOI for 24 hours. IFN-α (left panel) and IL-12 (right panel) were measured in the supernatants using ELISA. UV-inactivated KOS HSV-1 effectively stimulated IPCs sorted from splenocytes (data not shown).