Figure 5.
In vitro characterization of oxLDL uptake by NF-κB1-/- and wild-type macrophages. (A) Uptake of DiI-labeled oxLDL by wild-type and NF-κB1-/- macrophages. (B) Uptake of DiI-labeled oxLDL by wild-type and NF-κB1-deficient macrophages stimulated overnight with LPS before uptake. Expression of (C) scavenger receptor class A (SR-A) and (D) CD36 after indicated times of activation with LPS (10 ng/mL) was quantified using qPCR. Bars represent wild-type (□) and NF-κB1-/- (▧)) BM-derived macrophages. (A-B) Representative for 3 experiments. (C-D) Representative for 2 experiments. Error bars indicate SD.