GVT activity is preserved in recipients of LPAM α₄β₇ T cells. C57BL/6 mice received transplants with B10.BR donor cells as described in Figure 1. Recipients were given 1 × 10⁵ EL4 murine leukemia/lymphoma cells as a separate intravenous injection at the time of transplantation. Survival is depicted as a Kaplan-Meier curve representing mice that received TCD-BM only (n = 8), TCD-BM + EL4 (n = 8), TCD-BM + α₄β₇⁺ T cells + EL4 (n = 22), TCD-BM + α₄β₇^– T cells + EL4 (n = 22). Statistical analysis: ▴ versus ♦ P = .0009.