Figure 5.
Effects of CD62L– T cells on T-cell reconstitution after hematopoietic cell transplantation. T cells from congenic C57BL/6 CD45.1 mice were transplanted into lethally irradiated BALB/c mice along with C57BL/6 TCD BM. Reconstitution of T cells of different origins was followed by flow cytometric analysis. Only the P values from the comparison between CD62L– and TCD BM only are indicated. All values represent means ± SD. (A) Total CD4+; P < .05, except on day +14 and day +98. (B) Donor mature T cell–derived CD4+; P < .01. (C) Donor TCD BM–derived CD4+; P < .01 except on day +98. (D) Host-type CD4+; P < .01. (E) Total CD8+; P < .05 except on day +98. (F) Donor mature T cell–derived CD8+; P < .05. (G) Donor TCD BM–derived CD8+; P < .05 except on day +98. (H) Host-type CD8+; P < .01.