Long-term immune reconstitution of CD62L^– T-cell recipients. More than 100 days after transplantation, C3H/HeJ recipients of unprimed C57BL/6 CD62L^– T cells (Figure 3) were killed and peripheral blood and spleen cells were obtained for phenotypic and functional assays in comparison with TCD BM controls and normal mice. All values represent means ± SD. (A) Peripheral blood T-cell counts. (B) Percentages of naive T cells in peripheral blood. ⁺P < .05, compared with normal C57BL/6. (C) CD4⁺ T-cell repertoire. *P < .001, CD62L^– versus TCD BM; for Vβ3, P ≤ .0001, CD62L^– versus normal C57BL/6 or normal C3H/HeJ; for Vβ5.1/5.2, Vβ11, and Vβ12, P < .0001, CD62L^– versus normal C57BL/6. Similar results were observed on CD8⁺ T cells. (D) sjTREC assay. ^&P < .05, compared with other groups. (E) MLR assay. For C57BL/6 stimulator, P < .0001, CD62L^– versus normal C3H/HeJ; for BALB/c stimulator, P < .001, CD62L^– versus normal C57BL/6; for C3H/HeJ stimulator, P < .0001 CD62L^– versus normal C57BL/6.