Influence of permissive or nonpermissive HLA-DPB1 mismatches on the clinical outcome of unrelated HSC transplantation. The probability of overall grades II to IV aGvHD (A), TRM (B), relapse (C), or survival (D) was analyzed in 63 pairs with permissive (continuous line) and 24 or 31 pairs with nonpermissive HLA-DPB1 mismatches in GvH (dotted line) or HvG (dashed line) direction, respectively. The probabilities of overall survival and aGvHD were calculated according to Kaplan-Meier estimates; TRM and relapse were analyzed by cumulative incidence curves.