Figure 2.
Figure 2. Anergic HLILs dominantly suppress autologous PBMC responses. The vertical axis shows cytokine (IL-10 and IFN-γ) and proliferative responses measured after 5 days' stimulation. Separate cultures of HLILs and autologous PBMCs, and cultures containing a 1:1 mixture of both cell types, were stimulated with mitogen (ConA), recall antigen (PPD), or primary antigen (KLH). The results for samples from individual patients are linked by solid lines. Each patient (n = 10) is identified by a symbol: •, HL1; ▪, HL2; ▴, HL3; ▾, HL4; ♦, HL5; ⬡, HL6; ○, HL7; □, HL8; ▵, HL9; ▿, HL10.

Anergic HLILs dominantly suppress autologous PBMC responses. The vertical axis shows cytokine (IL-10 and IFN-γ) and proliferative responses measured after 5 days' stimulation. Separate cultures of HLILs and autologous PBMCs, and cultures containing a 1:1 mixture of both cell types, were stimulated with mitogen (ConA), recall antigen (PPD), or primary antigen (KLH). The results for samples from individual patients are linked by solid lines. Each patient (n = 10) is identified by a symbol: •, HL1; ▪, HL2; ▴, HL3; ▾, HL4; ♦, HL5; ⬡, HL6; ○, HL7; □, HL8; ▵, HL9; ▿, HL10.

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